Pharmaceutical Passivation, Cleaning & Flushing Services in Holly Springs, NC
CXP Solutions provides mobile ASTM A967/A380-compliant passivation, CIP cleaning, and pre-commissioning flushing for biotech and pharmaceutical facilities in Holly Springs and the surrounding RTP corridor. From WFI loops and purified water systems to process vessels and clean utility piping, we deliver audit-ready chemical cleaning and passivation built for GMP environments near facilities such as FUJIFILM Diosynth Biotechnologies, Amgen, and other Holly Springs life science sites*.
*Facilities referenced as examples of local industry only. CXP provides independent services and is not claiming affiliation or endorsement.
Built for Holly Springs Biotech, Pharma & Advanced Manufacturing
Holly Springs has rapidly become a core node in the RTP life science cluster, with large-scale biologics, vaccine, and advanced therapy facilities operating under strict GMP expectations. Those facilities rely on high-purity stainless steel systems—WFI, purified water, clean steam, CIP, and process vessels—that must stay within tight specification to avoid production risk and regulatory findings.
CXP mobilizes from our central hub in Sanford to provide fast-response passivation, cleaning, and flushing services specifically tuned to:
Typical Holly Springs Facility Types
Example facility profiles CXP is designed to support in the Holly Springs / RTP corridor:
CXP is an independent service provider supporting the broader Holly Springs/RTP life science ecosystem.
Passivation, Cleaning & Flushing Services We Provide in Holly Springs
From greenfield turnover to corrective derouging, CXP delivers full-lifecycle stainless steel care for Holly Springs facilities—plus the documentation your Quality team expects.
Citric Acid Passivation
ASTM A967-compliant citric formulations for WFI, PW, clean steam, CIP, and process piping. Full-system circulation or targeted hand passivation.
Alkaline CIP Cleaning
High-temperature alkaline pre-operational cleaning (POC) to remove fabrication oils, organic load, and construction debris, setting up a clean base for passivation.
High-Velocity Flushing
Pre-commissioning flushing for carbon steel and stainless utility loops to remove weld slag, scale, and construction fines prior to tie-in.
Rouge Removal & Derouging
EDTA-enhanced citric blends and derouging services to correct iron oxide contamination in WFI, PW, and clean steam systems.
Typical Systems We Clean & Passivate in Holly Springs
Whether you're starting up a new cell culture suite or expanding vaccine manufacturing, CXP builds a project-specific cleaning + passivation + flushing plan around your piping isometrics, P&IDs, and validation requirements.
How a Holly Springs Passivation & Flushing Project Runs
A six-phase process that starts at our Sanford hub and ends with FDA-ready documentation on your desk. Detailed protocols available in our ASTM A967 Passivation Guide.
Scope Review & Turnover Planning
We start with P&IDs, isometrics, URS, and existing SOPs to define a Holly Springs-specific cleaning and passivation plan. We coordinate around your SAT/FAT, commissioning, and validation schedule so chemical work doesn't become the critical path.
Mobilization from Sanford Hub
Our mobile CIP/passivation skid, pumps, hose sets, test equipment, and chemicals are staged in Sanford and mobilized into Holly Springs with pre-labeled connection points and routing plans to minimize on-site chaos and downtime.
Alkaline Cleaning & High-Velocity Flushing
We run high-temperature alkaline cleaning to remove fabrication residues, then flush until particle counts, turbidity, and visual inspections meet acceptance. For black utilities, we use heat exchanger and cold plate cleaning techniques where needed.
Citric Acid Passivation & Derouging
We apply citric acid passivation chemistry per ASTM A967, adjusting concentration, temperature, and contact time based on material finish, weld density, and pre-existing rouge. For localized issues, we combine with hand passivation at welds and dead legs.
Neutralization, Final Rinse & Verification Testing
We neutralize discharge, then rinse with WFI/RO/DI until pH, conductivity, and appearance are within spec. Verification includes water break tests, copper sulfate, ferroxyl, and visual inspection per ASTM A380.
Turnover Package & Quality Review
You receive a complete documentation package aligned with your Quality expectations: executed protocol, logs, test results, calibration certificates, chemical lot traceability, and before/after photos.
Sanford as Your Central Passivation Hub
Holly Springs is one of several life science clusters we support within a rapid deployment radius from Sanford— keeping mobilization time and costs predictable.
Planning a Project in Holly Springs?
Share your P&IDs, target turnover dates, and acceptance criteria. We'll build a Holly Springs-specific passivation, cleaning, and flushing plan your Quality and Engineering teams can sign off on.
Frequently Asked Questions – Holly Springs Services
What passivation services does CXP provide in Holly Springs NC?
Does CXP serve biotech facilities near FUJIFILM Diosynth and Amgen?
What systems does CXP clean and passivate in Holly Springs?
How quickly can CXP respond to Holly Springs projects?
Need Passivation, Cleaning or Flushing in Holly Springs, NC?
CXP Solutions provides specialized pharmaceutical and biotech passivation services from our Sanford hub to Holly Springs and the surrounding RTP corridor. Whether you're commissioning a new suite, correcting rouge, or tightening up validation ahead of an audit, we can design a focused, documented program around your facility.